Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development
) were detected in this study. The persistence of MTZ and SX in the aqueous environment was estimated at 14 to 139 days and 9 to 88 days, respectively. The single exposure to MTZ induced cardiotoxicity and changes in the swim bladder and tail curvature. MTZ and SX induced sensory and physiological morphometric changes compared to the control. MTZ, alone or combined with SX, affected the larvae's behavior. Our findings contribute to the understanding of the presence, persistence, and ecotoxicity of antimicrobials in aquatic environments.
Authors
- Valter Henrique Carvalho-Silva (ORCID: https://orcid.org/0000-0002-7411-0099)
- Elisa Flávia Luiz Cardoso Bailão (ORCID: https://orcid.org/0000-0001-6737-7548)
- Mirelle Garcia Silva‐Bailão (ORCID: https://orcid.org/0000-0003-2053-204X)
- Naiara Raica Lopes de Oliveira (ORCID: https://orcid.org/0009-0004-4475-205X)
- Felipe Cirqueira Dias
- Flávio O. Sanches-Neto (ORCID: https://orcid.org/0000-0002-0664-171X)
- Jéssyca Moreira Morais
- Jerônimo Raimundo de Oliveira Neto (ORCID: https://orcid.org/0000-0002-0261-4554)
- Thiago Lopes Rocha (ORCID: https://orcid.org/0000-0003-0551-6842)
- Lorranny Pereira de Assis Valadares (ORCID: https://orcid.org/0000-0003-4198-9567)
- Igor Romeiro dos Santos
- Náthala Maria Simão
- Luiz Carlos da Cunha
Institutions
- Universidade Estadual de Goiás (BR)
- Instituto Federal de Goiás (BR)
- Universidade Federal de Goiás (BR)
Publication Details
- Journal
- Environmental Toxicology
- Published
- 2026-04-30
- DOI
- https://doi.org/10.1002/tox.70100
- Primary Topic
- Pharmaceutical and Antibiotic Environmental Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Goiás