Development and Pilot Clinical Study of a Novel FAP-Targeted PET Tracer for PET Imaging of Tumors
F]AlF-AA-FAPT demonstrates excellent target-to-background ratio and improves pharmacokinetic properties, making it an effective alternative to current FAPI tracers.
Authors
- Zhanwen Zhang (ORCID: https://orcid.org/0000-0003-3877-5672)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Ying Liu (ORCID: https://orcid.org/0000-0002-1312-0146)
- Y Zhang
- Keyin Chen
- J Huang
- Ganghua Tang
- Rongqin Zhang
- Weijiang Liao
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-04-30
- DOI
- https://doi.org/10.1021/acs.analchem.5c07388
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Department of Education of Guangdong Province
- Basic and Applied Basic Research Foundation of Guangdong Province