Drug fever induced by Xingnaojing injection: A case report

RATIONALE: The application of Xingnaojing injection is widespread; however, drug-induced fever associated with this medication is challenging to diagnose. Previous literature rarely reports cases of drug-induced fever resulting from the use of Xingnaojing injection. PATIENT CONCERNS: A 46-year-old male patient, who underwent surgery for cerebral hemorrhage, presented with fever. The condition is considered to be drug fever induced by the administration of Xingnaojing. DIAGNOSES: Considering the potential for drug fever associated with the administration of Xingnaojing injection. INTERVENTIONS: Discontinue the use of Xingnaojing injection. OUTCOMES: The patient has shown improvement and is being discharged. LESSONS: Clinical practitioners should enhance the prevention and management of adverse drug reactions to reduce both patient hospitalization duration and economic costs, thereby ensuring the safety of medication use for patients.

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Publication Details

Journal
Medicine
Published
2026-05-01
DOI
https://doi.org/10.1097/md.0000000000048482
Primary Topic
Hematological disorders and diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Drug fever induced by Xingnaojing injection: A case report

Shaowei Xie, Ye Yuan, Bo Gao, Weiqian Liu et al.
Medicine
Hematological disorders and diagnostics
article

Drug fever induced by Xingnaojing injection: A case report

Shaowei Xie, Ye Yuan, Bo Gao, Weiqian Liu, Yu Yin
article en

Abstract

RATIONALE: The application of Xingnaojing injection is widespread; however, drug-induced fever associated with this medication is challenging to diagnose. Previous literature rarely reports cases of drug-induced fever resulting from the use of Xingnaojing injection. PATIENT CONCERNS: A 46-year-old male patient, who underwent surgery for cerebral hemorrhage, presented with fever. The condition is considered to be drug fever induced by the administration of Xingnaojing. DIAGNOSES: Considering the potential for drug fever associated with the administration of Xingnaojing injection. INTERVENTIONS: Discontinue the use of Xingnaojing injection. OUTCOMES: The patient has shown improvement and is being discharged. LESSONS: Clinical practitioners should enhance the prevention and management of adverse drug reactions to reduce both patient hospitalization duration and economic costs, thereby ensuring the safety of medication use for patients.

MedicineVol. 105(18)
Hebei General Hospital (CN)
Good health and well-being
Openalex Percentile: Top 12%
Hematological disorders and diagnostics
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Drug fever induced by Xingnaojing injection: A case report — Shaowei Xie, Ye Yuan, et al. · Medicine (2026) | TGRS Research Map | TGRS