Engineering Enantiocomplementary Protoglobins for Stereoconvergent Construction of <i>N</i> -Alkylated α-Aminoketones
transformations, facilitating the conversion of simple chemicals into an array of valuable pharmaceutical compounds featuring aminoketone functionalities.
Authors
- Frances H. Arnold (ORCID: https://orcid.org/0000-0002-4027-364X)
- Ziyang Qin
- Chi Zhang (ORCID: https://orcid.org/0000-0002-7422-2584)
- Zi‐Qi Li (ORCID: https://orcid.org/0009-0000-0469-8942)
- Sophia J. Wu (ORCID: https://orcid.org/0009-0007-2832-5826)
- K N Houk
- Runze Mao
- William A Goddard Iii
- Jan L Heise
Institutions
- California Institute of Technology (US)
- University of California, Los Angeles (US)
- Division of Chemistry (US)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1021/jacs.5c17989
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- California Institute of Technology
- Division of Chemical, Bioengineering, Environmental, and Transport Systems
- Basic Energy Sciences