<i>Escherichia coli</i> pathobionts and Crohn’s disease: varied genetic paths leading to similar phenotypes
, suggesting that some of these genetic features might account for particular LF82 phenotypes. In this review, we summarize changes in the CD gut, the association of AIEC with CD, genes and SNPs associated with AIEC, and recent work connecting a specific SNP within a bacterial RNA polymerase gene to the expression of genes associated with the LF82 lifestyle.
Authors
- Gregory J. Phillips (ORCID: https://orcid.org/0000-0002-0048-512X)
- Deborah M. Hinton (ORCID: https://orcid.org/0000-0002-7254-9495)
- Melissa Arroyo-Mendoza (ORCID: https://orcid.org/0000-0002-9461-1202)
- Hernán Lorenzi (ORCID: https://orcid.org/0000-0003-0910-7894)
Institutions
- University of Georgia (US)
- National Institute of Diabetes and Digestive and Kidney Diseases (US)
Publication Details
- Journal
- Journal of Bacteriology
- Published
- 2026-04-30
- DOI
- https://doi.org/10.1128/jb.00016-26
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health