Pulling the strings: Contractile VE-cadherin junctions to stabilize angiogenic sprouts
Dynamic yet stable endothelial interactions during angiogenesis remain poorly understood despite their importance in development and regeneration. Mayo et al. (https://doi.org/10.1083/jcb.202503146) identify Scribble and myosin-1c as key regulators of stable cell-cell junctions during angiogenic sprouting, coordinating junctional stability with vascular dynamics.
Authors
- Stephan Huveneers (ORCID: https://orcid.org/0000-0002-1091-475X)
Institutions
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- The Journal of Cell Biology
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1083/jcb.202603197
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hartstichting