PHARMACEUTICO-ANALYTICAL STANDARDIZATION OF SIDDAPANCHANANA RASA – A CLASSICAL HERBO-MINERAL

Background: Siddapanchanana Rasa, a classical herbo-mineral Kharaliyarasayana from Rasaprakasha Sudhakara for Prameha (Diabetes), lacks published Pharmaceutico-Analytical standardization. Methods: Prepared via classical Shodhana, 180-hour Kajjali Mardana (97.27% yield). Evaluated through Organoleptic, Physico-chemical (pH, ash values, particle size), XRD, and FTIR analysis. Results: Greenish-black powder, XRD confirmed HgS, FTIR showed phenolic O-H alkaloid CN (2162 cm⁻¹) signatures. Conclusion: Demonstrates reproducible quality parameters suitable for AYUSH pharmacopoeial standardization as Pramehaghna formulation.