A Case of Congenital Hypothyroidism in Cats: Diagnostic Challenges and Therapeutic Outcomes

This report presents a case of congenital hypothyroidism in a 3-year-old female Persian cat, a condition that is seldom encountered in feline patients. The cat was presented with chronic renal failure and stunted growth, exhibiting a unique combination of symptoms, including dwarfism, an abnormal skull shape and open growth plates. A complete blood count (CBC) identified moderate anaemia, while the biochemical analysis showed elevated serum creatinine levels and blood urea nitrogen (BUN) levels. Low serum total thyroxine (TT4) concentrations, both before and after the administration of thyroid-stimulating hormone (TSH), confirmed the presumptive diagnosis of congenital hypothyroidism. Following this, levothyroxine supplementation was initiated. After 1 week of therapy, the cat displayed decreased creatinine levels and increased activity. This case highlights that feline hypothyroidism, although rare, should be considered a differential diagnosis in similar cases.

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Publication Details

Journal
Veterinary Medicine and Science
Published
2026-04-30
DOI
https://doi.org/10.1002/vms3.70949
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case of Congenital Hypothyroidism in Cats: Diagnostic Challenges and Therapeutic Outcomes

Farkhondeh Fahim Dezhban, Amin Zamani, Morteza Ezati Kakalar, Sina Sabour Razlighi
Veterinary Medicine and Science
Thyroid Disorders and Treatments
article

A Case of Congenital Hypothyroidism in Cats: Diagnostic Challenges and Therapeutic Outcomes

Farkhondeh Fahim Dezhban, Amin Zamani, Morteza Ezati Kakalar, Sina Sabour Razlighi
article en

Abstract

This report presents a case of congenital hypothyroidism in a 3-year-old female Persian cat, a condition that is seldom encountered in feline patients. The cat was presented with chronic renal failure and stunted growth, exhibiting a unique combination of symptoms, including dwarfism, an abnormal skull shape and open growth plates. A complete blood count (CBC) identified moderate anaemia, while the biochemical analysis showed elevated serum creatinine levels and blood urea nitrogen (BUN) levels. Low serum total thyroxine (TT4) concentrations, both before and after the administration of thyroid-stimulating hormone (TSH), confirmed the presumptive diagnosis of congenital hypothyroidism. Following this, levothyroxine supplementation was initiated. After 1 week of therapy, the cat displayed decreased creatinine levels and increased activity. This case highlights that feline hypothyroidism, although rare, should be considered a differential diagnosis in similar cases.

Veterinary Medicine and ScienceVol. 12(3)
Islamic Azad University of Garmsar (IR), Islamic Azad University, Karaj (IR), University of Tehran (IR)
Zero hunger
Openalex Percentile: Top 12%
Thyroid Disorders and Treatments
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