How pharmacokinetic/pharmacodynamic models can inform the development of new HIV medications
There remains a need for new HIV medications. This has been challenged by the increasing costs associated with drug discovery and testing. One solution to this issue involves the incorporation of pharmacokinetic/pharmacodynamic (PK/PD) models into the development pipeline. This article provides an overview of how PK/PD models can be used to provide insights to aid this endeavour. This article is part of the Theo Murphy meeting issue 'Evaluating anti-infective drugs'.
Authors
- Saye Khoo (ORCID: https://orcid.org/0000-0002-2769-0967)
- Shawn Edgar Miranda
Institutions
- University of Liverpool (GB)
Publication Details
- Journal
- Philosophical Transactions of the Royal Society B Biological Sciences
- Published
- 2026-04-30
- DOI
- https://doi.org/10.1098/rstb.2024.0342
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research