Caffeic Acid Protects Keratinocytes from PM <sub>2.5</sub> by Regulating ROS, Mitochondrial Integrity, and JNK Activation
-induced oxidative stress and apoptosis by regulating the Bcl-2/Bax axis and inhibiting JNK-mediated apoptotic signaling, highlighting its potential as a therapeutic candidate for preventing pollutant-induced skin damage.
Authors
- Mei Jing Piao
- Kyoung Ah Kang (ORCID: https://orcid.org/0000-0002-5382-536X)
- Jinny Park (ORCID: https://orcid.org/0009-0005-3186-3591)
- Herath Mudiyanselage Maheshika Madhuwanthi Senavirathna
- J W Hyun
- Mahadurage Pasindu Laksara Madhuwantha
Institutions
- Korea University (KR)
- Jeju National University (KR)
Publication Details
- Journal
- Biomolecules & Therapeutics
- Published
- 2026-04-30
- DOI
- https://doi.org/10.4062/biomolther.2025.254
- Primary Topic
- Bee Products Chemical Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education
- National Research Foundation of Korea