Antibacterial Activity of Quince (Cydonia oblonga Miller) Extracts Against Some Pathogens Isolated from Laryngitis

Background: Antimicrobial resistance has emerged as a major global health challenge, prompting the search for novel antimicrobial agents. Natural products, including quince (Cydonia oblonga Miller), are rich in bioactive compounds with potential therapeutic properties. Objective: To evaluate the antibacterial activity of aqueous and ethanolic extracts of quince fruit against pathogenic bacteria isolated from patients with laryngitis. Methods: Swab samples were collected from patients with laryngitis and cultured on selective media to isolate Gram-positive and Gram-negative bacteria. Isolates were identified using the VITEK system. Quince fruit extracts (aqueous and ethanolic) were prepared at concentrations of 25, 50, and 75 mg/mL and tested for antibacterial activity using the agar well diffusion method. Results: The predominant isolates included Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The ethanolic extract demonstrated the highest antibacterial activity, particularly against S. aureus (12 mm inhibition zone), followed by E. coli (9 mm) and P. aeruginosa (8 mm). The aqueous extract exhibited comparatively lower activity but followed the same sensitivity pattern. Conclusion: Quince fruit extracts exhibit notable antibacterial activity, with ethanolic extracts showing superior efficacy. These findings suggest potential applications in antimicrobial therapy and food preservation.