SANGYASTHAPAK GANA DHOOPAN VARTI: A COMPREHENSIVE STUDY ON ITS NEURO-MODULATORY ROLE IN THE MANAGEMENT OF AUTISM SPECTRUM DISORDER (ASD)

Background: Autism Spectrum Disorder (ASD) involves complex neuro-psychological deficits where oral drug delivery is often hindered by sensory aversions. Dhoopana Karma (medicated fumigation) using Sangyasthapak Gana offers a non-invasive, nasal-to-brain delivery system. Objective: To evaluate the therapeutic potential, phytochemical basis, and pharmaceutical preparation of Sangyasthapak Gana Dhoopa Varti in managing pediatric autism. Methods: A review of classical texts (Charaka Samhita, Kashyapa Samhita) and modern databases was conducted. A standardized method for preparing Dhoopa Varti (medicated wicks) was developed. Results: Phytochemicals like Bacosides, Asarones, and Jatamansone bypass the blood-brain barrier via the olfactory pathway, modulating GABA-ergic and cholinergic systems to reduce hyperactivity and enhance cognition. Conclusion: Sangyasthapak Dhoopana is a safe, scientifically sound adjunct therapy for neuro-psychological stabilization in ASD.