Channelopathy linking <i>KCNH2</i> mutation and primary aldosteronism: a case of life-threatening torsades de pointes
, consistent with congenital long QT syndrome type 2 (LQTS2). A review of the literature identified 16 previously reported cases of PA-associated ventricular arrhythmia, which showed a consistent association with hypokalemia and hypertension; however, none included genetic evaluation. This case highlights the need for parallel endocrine and arrhythmia evaluation in patients with unexplained ventricular arrhythmias.
Authors
- Padiporn Limumpornpetch (ORCID: https://orcid.org/0000-0003-2205-3616)
- Pongsakorn Choochuen (ORCID: https://orcid.org/0000-0002-0739-3885)
- Wongsakorn Chaochankit (ORCID: https://orcid.org/0000-0003-2202-7426)
- Sunti Limumpornpetch (ORCID: https://orcid.org/0009-0008-7222-232X)
- Watchara Lohawijarn (ORCID: https://orcid.org/0000-0002-7229-375X)
- Saran Dejprapasorn
Institutions
- Prince of Songkla University (TH)
Publication Details
- Journal
- JCEM Case Reports
- Published
- 2026-04-11
- DOI
- https://doi.org/10.1210/jcemcr/luag123
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00