Risk Factors Associated With Delayed Secretory Activation in a Cohort of Nulliparous Women in Western Australia

BACKGROUND: Delayed secretory activation can negatively impact maternal and child health through increasing the risk of early cessation of breastfeeding. Early cessation of breastfeeding is known to be associated with increased health risks. AIM: To determine the occurrence of, and risk factors associated with, delayed secretory activation in nulliparous women in Western Australia. METHODS: ≤ 0.10) were entered into binary logistic regression models to quantify their association with delayed secretory activation and adjusted for known confounders. RESULTS: : OR 2.51 (95% CI 1.13, 5.55), and gestational diabetes mellitus (GDM): OR (5.06; 95% CI 1.28, 20.08) in bivariate analysis and in the adjusted multivariable model. Among mothers with GDM, 78.6% experienced delayed secretory activation, compared to 21.4% of mothers who did not have GDM. CONCLUSION: Nulliparous women, particularly those with GDM, should be supported to initiate early, frequent, and optimal breast stimulation to exclusively breastfeed.

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Publication Details

Journal
Journal of Human Lactation
Published
2026-04-27
DOI
https://doi.org/10.1177/08903344261435721
Primary Topic
Breastfeeding Practices and Influences
Type
article
Field-Weighted Citation Impact
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article

Risk Factors Associated With Delayed Secretory Activation in a Cohort of Nulliparous Women in Western Australia

Roslyn Giglia, Anita M. Moorhead, Deborah Ireson, Matthew N. Cooper et al.
Journal of Human Lactation
Breastfeeding Practices and Influences
article

Risk Factors Associated With Delayed Secretory Activation in a Cohort of Nulliparous Women in Western Australia

Roslyn Giglia, Anita M. Moorhead, Deborah Ireson, Matthew N. Cooper, Cassandra Cuffe, Julie Hill, Therese O'Sullivan, Joshua R. Lewis
article en

Abstract

BACKGROUND: Delayed secretory activation can negatively impact maternal and child health through increasing the risk of early cessation of breastfeeding. Early cessation of breastfeeding is known to be associated with increased health risks. AIM: To determine the occurrence of, and risk factors associated with, delayed secretory activation in nulliparous women in Western Australia. METHODS: ≤ 0.10) were entered into binary logistic regression models to quantify their association with delayed secretory activation and adjusted for known confounders. RESULTS: : OR 2.51 (95% CI 1.13, 5.55), and gestational diabetes mellitus (GDM): OR (5.06; 95% CI 1.28, 20.08) in bivariate analysis and in the adjusted multivariable model. Among mothers with GDM, 78.6% experienced delayed secretory activation, compared to 21.4% of mothers who did not have GDM. CONCLUSION: Nulliparous women, particularly those with GDM, should be supported to initiate early, frequent, and optimal breast stimulation to exclusively breastfeed.

Journal of Human Lactation
Edith Cowan University (AU), The University of Sydney (AU), Royal Women's Hospital (AU), The University of Western Australia (AU), La Trobe University (AU), Children's Hospital at Westmead (AU), Charles Darwin University (AU)
Good health and well-being
Openalex Percentile: Top 6%
Breastfeeding Practices and Influences
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