Wiskott–Aldrich Syndrome: A Rare X-Linked Immunodeficiency Disorder and Its Clinical Implications

Thrombocytopenia, eczema, and recurring infections are the typical trifecta of Wiskott-Aldrich Syndrome (WAS), a rare X-linked recessive immunodeficiency condition. Due to abnormalities in the WAS gene, which produces the Wiskott–Aldrich Syndrome protein (WASP), which is essential for immune cell function, it mainly affects male children. Immune dysregulation, bleeding tendencies, and an increased vulnerability to infections and cancer are the outcomes of the syndrome. Improving survival and quality of life requires early diagnosis and effective treatment. While supportive therapies assist control symptoms and avoid problems, hematopoietic stem cell transplantation is thought to be the final treatment. This article examines Wiskott-Aldrich Syndrome's etiology, pathophysiology, clinical symptoms, diagnostic techniques, management modalities, and nursing implications.