Case Report: A rare case of EBV-positive inflammatory follicular dendritic cell sarcoma occurring in the testes

Follicular dendritic cell sarcoma (FDCS) is an exceedingly rare low-grade malignant tumor originating from follicular dendritic cells. It is classified into two subtypes: the classic type and the EBV-positive inflammatory follicular dendritic cell sarcoma (EBV+ iFDCS). While EBV+ iFDCS predominantly arises in abdominal organs such as the liver and spleen, its morphological spectrum is broad, rendering diagnosis challenging. Here, we report an exceptionally rare case of EBV+ iFDCS occurring in the testes, a site previously unreported in the literature.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-04-28
DOI
https://doi.org/10.3389/fonc.2026.1723376
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Case Report: A rare case of EBV-positive inflammatory follicular dendritic cell sarcoma occurring in the testes

Rongrong Meng, Zhengzheng Shi, Xuefen Wang
Frontiers in Oncology
Histiocytic Disorders and Treatments
article

Case Report: A rare case of EBV-positive inflammatory follicular dendritic cell sarcoma occurring in the testes

Rongrong Meng, Zhengzheng Shi, Xuefen Wang
article en

Abstract

Follicular dendritic cell sarcoma (FDCS) is an exceedingly rare low-grade malignant tumor originating from follicular dendritic cells. It is classified into two subtypes: the classic type and the EBV-positive inflammatory follicular dendritic cell sarcoma (EBV+ iFDCS). While EBV+ iFDCS predominantly arises in abdominal organs such as the liver and spleen, its morphological spectrum is broad, rendering diagnosis challenging. Here, we report an exceptionally rare case of EBV+ iFDCS occurring in the testes, a site previously unreported in the literature.

Frontiers in OncologyVol. 16
Integrated Chinese Medicine (China) (HK)
Good health and well-being
Openalex Percentile: Top 11%
Histiocytic Disorders and Treatments
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