Distal symmetric diabetic neuropathy

1 Within 10 years of diagnosis, 40% to 50% of people with type 1 (T1D) or type 2 diabetes (T2D) develop peripheral sensorimotor polyneuropathy 1,2 Damage to sensory nerve fibres can cause symptoms including progressive sensory loss in the extremities, sharp or shooting pain, dysesthesias (burning or tingling sensations), and paresthesia (e.g., numbness). 1Although neuronal loss cannot be reversed, glucose control can help to prevent diabetic peripheral neuropathy in people with T1D and slow progression of neuropathy in people with T2D. 2

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Publication Details

Journal
Canadian Medical Association Journal
Published
2026-04-26
DOI
https://doi.org/10.1503/cmaj.251358
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Distal symmetric diabetic neuropathy

H. Beric Wright, Eric Henderson, Rajive Jassal
Canadian Medical Association Journal
Diabetic Foot Ulcer Assessment and Management
article

Distal symmetric diabetic neuropathy

H. Beric Wright, Eric Henderson, Rajive Jassal
article en

Abstract

1 Within 10 years of diagnosis, 40% to 50% of people with type 1 (T1D) or type 2 diabetes (T2D) develop peripheral sensorimotor polyneuropathy 1,2 Damage to sensory nerve fibres can cause symptoms including progressive sensory loss in the extremities, sharp or shooting pain, dysesthesias (burning or tingling sensations), and paresthesia (e.g., numbness). 1Although neuronal loss cannot be reversed, glucose control can help to prevent diabetic peripheral neuropathy in people with T1D and slow progression of neuropathy in people with T2D. 2

Canadian Medical Association JournalVol. 198(16)
Western University (CA), University of Alberta (CA)
Openalex Percentile: Top 7%
Diabetic Foot Ulcer Assessment and Management
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