Distal symmetric diabetic neuropathy
1 Within 10 years of diagnosis, 40% to 50% of people with type 1 (T1D) or type 2 diabetes (T2D) develop peripheral sensorimotor polyneuropathy 1,2 Damage to sensory nerve fibres can cause symptoms including progressive sensory loss in the extremities, sharp or shooting pain, dysesthesias (burning or tingling sensations), and paresthesia (e.g., numbness). 1Although neuronal loss cannot be reversed, glucose control can help to prevent diabetic peripheral neuropathy in people with T1D and slow progression of neuropathy in people with T2D. 2
Authors
- H. Beric Wright
- Eric Henderson (ORCID: https://orcid.org/0000-0001-9188-5630)
- Rajive Jassal
Institutions
- Western University (CA)
- University of Alberta (CA)
Publication Details
- Journal
- Canadian Medical Association Journal
- Published
- 2026-04-26
- DOI
- https://doi.org/10.1503/cmaj.251358
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00