Traditional and Pharmacological Relevance of Cassia fistula- Aragvadha in Chronic Wound Healing: An Evidence-Based Review

Ethnopharmacological relevance: Cassia fistula Linn. (Āragvadha) is widely used in traditional systems of medicine, particularly Ayurveda, for the management of skin diseases, inflammation, and wounds. Chronic non-healing ulcers represent a major clinical challenge globally, highlighting the need for safe and effective plant-based therapeutic options.Aim of the study:To critically evaluate the traditional uses, phytochemistry, and pharmacological evidence of Cassia fistula, with special emphasis on its potential role in chronic wound healing.Materials and methods:A comprehensive literature review was conducted using classical Ayurvedic texts and electronic databases including PubMed and Google Scholar. Keywords such as “Cassia fistula,” “wound healing,” “antimicrobial,” “antioxidant,” and “ethnopharmacology” were used. Relevant peer-reviewed articles and classical references were included.Results:Cassia fistula exhibits significant antimicrobial, anti-inflammatory, antioxidant, and wound healing properties. Its bioactive constituents, including anthraquinones, flavonoids and tannins contribute to these effects. Traditional usage aligns with modern pharmacological findings, indicating its potential in managing chronic wounds.Conclusion:The available evidence supports the ethnopharmacological relevance of Cassia fistula in chronic wound management. Further well-designed experimental and clinical studies are required to validate its therapeutic potential.