Adverse Events of Saffron ( <i>Crocus sativus</i> L.): Systematic Review of Current Evidence

Background: , including stigma powder and other extracts, to evaluate their safety. Methods: " for clinical trials, case reports, and case series. Results: consumption is around 17.5%. The most frequently reported side effects were gastrointestinal problems, which were minor and self-limiting in most cases. Conclusion: is generally well tolerated. However, due to some potentially significant adverse events associated with its medicinal use at higher doses or prolonged administration, clinical monitoring should be considered.