Deep Learning-Based Protein Half-Life Prediction for Identifying Rate-Limiting Enzymes in Metabolic Pathways to Alleviate Bottleneck Reactions

prediction of enzyme half-life. This approach provides a viable strategy for alleviating metabolic bottlenecks, ultimately enhancing metabolic productivity.

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Publication Details

Journal
Journal of Microbiology and Biotechnology
Published
2026-04-27
DOI
https://doi.org/10.4014/jmb.2601.01071
Primary Topic
Machine Learning in Bioinformatics
Type
article
Field-Weighted Citation Impact
0.00

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article

Deep Learning-Based Protein Half-Life Prediction for Identifying Rate-Limiting Enzymes in Metabolic Pathways to Alleviate Bottleneck Reactions

Hyang‐Mi Lee, Y N Lee, Dokyun Na, Jingyu Lee et al.
Journal of Microbiology and Biotechnology
Machine Learning in Bioinformatics
article

Deep Learning-Based Protein Half-Life Prediction for Identifying Rate-Limiting Enzymes in Metabolic Pathways to Alleviate Bottleneck Reactions

Hyang‐Mi Lee, Y N Lee, Dokyun Na, Jingyu Lee, Yubin Kim, So Hee Oh, Youngseo Chang, Minh Thi-Hong Tran, Jun Ren
article en

Abstract

prediction of enzyme half-life. This approach provides a viable strategy for alleviating metabolic bottlenecks, ultimately enhancing metabolic productivity.

Journal of Microbiology and BiotechnologyVol. 36
Chung-Ang University (KR)
National Research Foundation, Chung-Ang University, National Research Foundation of Korea, Ministry of Science and ICT, South Korea
Decent work and economic growth
Openalex Percentile: Top 9%
Machine Learning in Bioinformatics
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