Designing Trustworthy AI Visualizations in High-Stakes Clinical Decision-Making: A Human-Centered Study of Visualization, Infrastructure, and Workflow

AI systems are increasingly deployed in health settings to assist with diagnosis, screening, triage, and physiological monitoring, yet little attention has been paid to how their outputs are visually communicated to users. This paper presents a qualitative, interface-centered comparative analysis of six publicly accessible AI health tools - SkinVision, Infermedica, Aysa, Qure.ai, Anura, and PMcardio evaluated through a Trust and Infrastructure Coding Frame derived from the Microsoft HAX guidelines and grounded in three user personas. Four cross-cutting themes emerge: visual clarity creates an illusion of certainty, explanation is consistently weaker than presentation, different modalities produce different trust dynamics, and infrastructure signals are routinely hidden. The paper introduces the High-Stakes AI Visualization Framework, a set of six design principles, and demonstrates its application through critical redesigns of three failure cases. The framework argues that trust calibration, not trust maximization, should guide health AI interface design.

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Publication Details

Journal
UNC Libraries
Published
2026-04-28
DOI
https://doi.org/10.17615/d314-2m52
Primary Topic
Data Visualization and Analytics
Type
article
Field-Weighted Citation Impact
0.00
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article

Designing Trustworthy AI Visualizations in High-Stakes Clinical Decision-Making: A Human-Centered Study of Visualization, Infrastructure, and Workflow

Dev Gandhi
UNC Libraries
Data Visualization and Analytics
article

Designing Trustworthy AI Visualizations in High-Stakes Clinical Decision-Making: A Human-Centered Study of Visualization, Infrastructure, and Workflow

Dev Gandhi
article en

Abstract

AI systems are increasingly deployed in health settings to assist with diagnosis, screening, triage, and physiological monitoring, yet little attention has been paid to how their outputs are visually communicated to users. This paper presents a qualitative, interface-centered comparative analysis of six publicly accessible AI health tools - SkinVision, Infermedica, Aysa, Qure.ai, Anura, and PMcardio evaluated through a Trust and Infrastructure Coding Frame derived from the Microsoft HAX guidelines and grounded in three user personas. Four cross-cutting themes emerge: visual clarity creates an illusion of certainty, explanation is consistently weaker than presentation, different modalities produce different trust dynamics, and infrastructure signals are routinely hidden. The paper introduces the High-Stakes AI Visualization Framework, a set of six design principles, and demonstrates its application through critical redesigns of three failure cases. The framework argues that trust calibration, not trust maximization, should guide health AI interface design.

UNC Libraries
University of North Carolina at Chapel Hill (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 4%
Data Visualization and Analytics
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