Human astrovirus draft genomes from under-five children presenting with gastroenteritis in Malawi from 2012 to 2024
Human astroviruses (HAstVs) account for 2% to 9% of gastroenteritis cases in children and are occasionally associated with central nervous system complications. We report six draft HAstV genomes from Malawian children <5 years old with gastroenteritis, providing baseline information for the understanding of HAstV diversity and disease burden in sub-Saharan Africa.
Authors
- Hlengiwe Sondlane (ORCID: https://orcid.org/0000-0002-4973-5281)
- End Chinyama (ORCID: https://orcid.org/0000-0003-2506-293X)
- Milton T. Mogotsi (ORCID: https://orcid.org/0000-0002-6755-1945)
- Chrispin Chaguza (ORCID: https://orcid.org/0000-0002-2108-1757)
- Benjamin Kumwenda (ORCID: https://orcid.org/0000-0002-5775-7528)
- Martin M. Nyaga (ORCID: https://orcid.org/0000-0002-5017-5584)
- Khuzwayo C. Jere (ORCID: https://orcid.org/0000-0003-3376-8529)
- Chimwemwe Mhango (ORCID: https://orcid.org/0000-0002-8769-7730)
- Celeste M. Donato (ORCID: https://orcid.org/0000-0001-9262-6550)
- Ernest Matambo (ORCID: https://orcid.org/0009-0000-8428-4036)
- Arox W. Kamng’ona (ORCID: https://orcid.org/0000-0002-0841-7586)
- Josephine Msowoya
- Flywell Kawonga (ORCID: https://orcid.org/0009-0000-7105-5015)
- Francis E. Dennis
- Prisca Benedicto Matambo
- Ayodeji E. Ogunbayo
- Nkosazana Shange
- Clara Majengo
Institutions
- St. Jude Children's Research Hospital (US)
- University of Liverpool (GB)
- The University of Melbourne (AU)
- University of Health Science (KH)
- University of Health and Allied Sciences (GH)
- University of the Free State (ZA)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- Kamuzu Central Hospital (MW)
- Noguchi Memorial Institute for Medical Research (GH)
- Murdoch Children's Research Institute (AU)
- Respiratory and Meningeal Pathogens Research Unit (ZA)
- Queen Elizabeth Central Hospital (MW)
- Health Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool (GB)
- Kamuzu University of Health Sciences (MW)
- University College London (GB)
Publication Details
- Journal
- Microbiology Resource Announcements
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1128/mra.01289-25
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation