Development of an ion-pairing reagent-assisted LC–MS/MS method employing fragmentation with stepped collision energy for monophosphoryl lipid A containing 3-deoxy-D-manno-octulosonic acid and its derivatives
-lipid A species, with potential to elucidate biosynthetic variations and establish a foundation for engineering lipid A analogs as next-generation LPS-based vaccine adjuvants.
Authors
- Hak Suk Chung (ORCID: https://orcid.org/0000-0003-1166-9909)
- 오한빈
- Jiyeong Hong (ORCID: https://orcid.org/0009-0006-3095-785X)
- Hyunjung Jin
- Kihun Kim (ORCID: https://orcid.org/0000-0002-0962-1837)
- Jihyun Yoon
Institutions
- Sogang University (KR)
- Bio-Medical Science (South Korea) (KR)
- Korea Institute of Science and Technology (KR)
- Korea University of Science and Technology (KR)
Publication Details
- Journal
- Journal of Chromatography A
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1016/j.chroma.2026.467040
- Primary Topic
- Mass Spectrometry Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Korea Foundation for Women In Science, Engineering and Technology
- Korea Institute of Science and Technology
- National Research Foundation of Korea