Yoga for Patients Undergoing Thoracic Radiotherapy and Their Family Caregivers: Results of a Randomized Controlled Trial
PURPOSE: Patients with advanced thoracic cancers undergoing standard radiotherapy (RT) have a high risk of experiencing performance declines and poor quality of life (QOL). Exercise programs may improve objective and subjective performance; yet, adherence remains poor. Including family caregivers as active intervention, participants may improve adherence and thus efficacy. Thus, this clinical trial seeks to examine the efficacy of a patient-caregiver dyadic yoga intervention relative to a dose-matched education/support (ES) intervention. MATERIALS AND METHODS: Patients with lung or esophageal cancer undergoing at least 5 weeks of RT and their family caregivers were randomly assigned to either a 15-session yoga or ES comparison intervention. Patients and caregivers were assessed at baseline (T1), the last day of RT (T2) and 1 (T3), 2 (T4), and 3 (T5) months later. Patients completed the 6-minute walk test (6MWT; primary outcome) and both patients and caregivers completed a validated QOL measure (secondary outcomes). RESULTS: = .02). CONCLUSION: Yoga significantly improves functional capacity and subjective physical QOL in patients undergoing thoracic RT. Involving a family caregiver may improve intervention adherence.
Authors
- Kathrin Milbury (ORCID: https://orcid.org/0000-0003-2605-3592)
- Scherezade K. Mama (ORCID: https://orcid.org/0000-0003-1935-7707)
- Jason R. Bentley (ORCID: https://orcid.org/0000-0002-9752-1958)
- Vickie R. Shannon (ORCID: https://orcid.org/0000-0002-5938-4841)
- Anne S. Tsao (ORCID: https://orcid.org/0000-0003-0505-6639)
- Eduardo D Bruera (ORCID: https://orcid.org/0000-0002-8745-0412)
- Meagan Whisenant (ORCID: https://orcid.org/0000-0002-9791-1227)
- Rosangela F. Silva
- Zhongxing Liao (ORCID: https://orcid.org/0000-0002-2224-9478)
- Yisheng Li (ORCID: https://orcid.org/0000-0001-9847-8544)
- Lorenzo Cohen (ORCID: https://orcid.org/0000-0001-7366-0518)
- Aileen Chen
- Sania Yousuf
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- The University of Texas Health Science Center (US)
- University of Houston - Clear Lake (US)
Publication Details
- Journal
- JCO Oncology Practice
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1200/op-25-01079
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 0.00