Yoga for Patients Undergoing Thoracic Radiotherapy and Their Family Caregivers: Results of a Randomized Controlled Trial

PURPOSE: Patients with advanced thoracic cancers undergoing standard radiotherapy (RT) have a high risk of experiencing performance declines and poor quality of life (QOL). Exercise programs may improve objective and subjective performance; yet, adherence remains poor. Including family caregivers as active intervention, participants may improve adherence and thus efficacy. Thus, this clinical trial seeks to examine the efficacy of a patient-caregiver dyadic yoga intervention relative to a dose-matched education/support (ES) intervention. MATERIALS AND METHODS: Patients with lung or esophageal cancer undergoing at least 5 weeks of RT and their family caregivers were randomly assigned to either a 15-session yoga or ES comparison intervention. Patients and caregivers were assessed at baseline (T1), the last day of RT (T2) and 1 (T3), 2 (T4), and 3 (T5) months later. Patients completed the 6-minute walk test (6MWT; primary outcome) and both patients and caregivers completed a validated QOL measure (secondary outcomes). RESULTS: = .02). CONCLUSION: Yoga significantly improves functional capacity and subjective physical QOL in patients undergoing thoracic RT. Involving a family caregiver may improve intervention adherence.

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Publication Details

Journal
JCO Oncology Practice
Published
2026-04-27
DOI
https://doi.org/10.1200/op-25-01079
Primary Topic
Cancer survivorship and care
Type
article
Field-Weighted Citation Impact
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article

Yoga for Patients Undergoing Thoracic Radiotherapy and Their Family Caregivers: Results of a Randomized Controlled Trial

Kathrin Milbury, Scherezade K. Mama, Jason R. Bentley, Vickie R. Shannon et al.
JCO Oncology Practice
Cancer survivorship and care
article

Yoga for Patients Undergoing Thoracic Radiotherapy and Their Family Caregivers: Results of a Randomized Controlled Trial

Kathrin Milbury, Scherezade K. Mama, Jason R. Bentley, Vickie R. Shannon, Anne S. Tsao, Eduardo D Bruera, Meagan Whisenant, Rosangela F. Silva, Zhongxing Liao, Yisheng Li, Lorenzo Cohen, Aileen Chen, Sania Yousuf
article en

Abstract

PURPOSE: Patients with advanced thoracic cancers undergoing standard radiotherapy (RT) have a high risk of experiencing performance declines and poor quality of life (QOL). Exercise programs may improve objective and subjective performance; yet, adherence remains poor. Including family caregivers as active intervention, participants may improve adherence and thus efficacy. Thus, this clinical trial seeks to examine the efficacy of a patient-caregiver dyadic yoga intervention relative to a dose-matched education/support (ES) intervention. MATERIALS AND METHODS: Patients with lung or esophageal cancer undergoing at least 5 weeks of RT and their family caregivers were randomly assigned to either a 15-session yoga or ES comparison intervention. Patients and caregivers were assessed at baseline (T1), the last day of RT (T2) and 1 (T3), 2 (T4), and 3 (T5) months later. Patients completed the 6-minute walk test (6MWT; primary outcome) and both patients and caregivers completed a validated QOL measure (secondary outcomes). RESULTS: = .02). CONCLUSION: Yoga significantly improves functional capacity and subjective physical QOL in patients undergoing thoracic RT. Involving a family caregiver may improve intervention adherence.

JCO Oncology Practice
The University of Texas MD Anderson Cancer Center (US), The University of Texas Health Science Center (US), University of Houston - Clear Lake (US)
No poverty
Openalex Percentile: Top 13%
Cancer survivorship and care
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