Heat-Killed <i>Lacticaseibacillus paracasei</i> HY2782 Attenuates Chronic Kidney Disease by Suppressing Inflammation and Selectively Modulating the Gut Microbial Community

, and correlation analysis further indicated that these taxa were associated with renal dysfunction and inflammatory markers. Collectively, these findings suggest that heat-killed HY2782 attenuates adenine-induced CKD in association with suppression of renal and intestinal inflammation and selective modulation of gut microbiota, supporting its potential as a postbiotic candidate for CKD management.

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Publication Details

Journal
Journal of Microbiology and Biotechnology
Published
2026-04-24
DOI
https://doi.org/10.4014/jmb.2603.03043
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Heat-Killed Lacticaseibacillus paracasei HY2782 Attenuates Chronic Kidney Disease by Suppressing Inflammation and Selectively Modulating the Gut Microbial Community

Joo-Yun Kim, Jae-Hwan Lee, Hyeonji Kim, Ji-Woong Jeong et al.
Journal of Microbiology and Biotechnology
Gut microbiota and health
article

Heat-Killed Lacticaseibacillus paracasei HY2782 Attenuates Chronic Kidney Disease by Suppressing Inflammation and Selectively Modulating the Gut Microbial Community

Joo-Yun Kim, Jae-Hwan Lee, Hyeonji Kim, Ji-Woong Jeong, Jae-Jung Shim
article en

Abstract

, and correlation analysis further indicated that these taxa were associated with renal dysfunction and inflammatory markers. Collectively, these findings suggest that heat-killed HY2782 attenuates adenine-induced CKD in association with suppression of renal and intestinal inflammation and selective modulation of gut microbiota, supporting its potential as a postbiotic candidate for CKD management.

Journal of Microbiology and BiotechnologyVol. 36
Hyosung Corporation (South Korea) (KR)
Good health and well-being
Openalex Percentile: Top 9%
Gut microbiota and health
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