Heat-Killed <i>Lacticaseibacillus paracasei</i> HY2782 Attenuates Chronic Kidney Disease by Suppressing Inflammation and Selectively Modulating the Gut Microbial Community
, and correlation analysis further indicated that these taxa were associated with renal dysfunction and inflammatory markers. Collectively, these findings suggest that heat-killed HY2782 attenuates adenine-induced CKD in association with suppression of renal and intestinal inflammation and selective modulation of gut microbiota, supporting its potential as a postbiotic candidate for CKD management.
Authors
- Joo-Yun Kim (ORCID: https://orcid.org/0000-0002-8864-0592)
- Jae-Hwan Lee
- Hyeonji Kim
- Ji-Woong Jeong
- Jae-Jung Shim
Institutions
- Hyosung Corporation (South Korea) (KR)
Publication Details
- Journal
- Journal of Microbiology and Biotechnology
- Published
- 2026-04-24
- DOI
- https://doi.org/10.4014/jmb.2603.03043
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00