A higher dietary inflammation index is associated with the incidence of overactive bladder: Evidence from a cross-sectional study (NHANES 2011–2018)

Current research has demonstrated that the development of overactive bladder (OAB) is related to the inflammatory response within the organism, and that this inflammatory response is closely associated with dietary factors; Accordingly, the purpose of this study was to investigate the connection between OAB and the dietary inflammatory index (DII). This cross-sectional analysis was based on data drawn from the National Health and Nutrition Examination Survey (NHANES) spanning the years 2011 to 2018, which included 21,263 participants (50.6% female, 49.4% male). The mean age of participants was 50.5 years, with the racial/ethnic distribution as follows: 42.9% non-Hispanic White, 21.1% non-Hispanic Black, 13.9% Mexican American, and 22.1% from other racial/ethnic groups. We employed weighted multiple logistic regression to analyze the correlation between DII and OAB, adjusting for potential confounders. This study comprised 21,263 people from the NHANES dataset. Following adjustment for all potential confounding variables, a positive association was observed between DII and the risk of OAB (OR 1.18, 95% CI 1.16-1.21). Smoothed curve fitting indicated a nonlinear correlation between DII and OAB, with an inflection point at 1.92. Stratified analyses demonstrated that this correlation was stable across different population subgroups. This study identified a significant nonlinear association between DII and OAB syndrome, suggesting that DII may serve as a useful indicator for predicting and diagnosing OAB.