Fourier Kolmogorov-Arnold Network integrated into BioBERT-based model for Biomedical Named Entity Recognition

Biomedical Named Entity Recognition (BioNER) extracts entities such as diseases, drugs, and genes from biomedical texts, which are often dense in domain-specific terms and complex semantics. Here, we present FRKAN-BioNER, a model designed to improve the efficiency of data mining in the biomedical field and support the development of precision medicine knowledge graphs. FRKAN-BioNER integrates BioBERT (Bidirectional Encoder Representations from Transformers for Biomedical Text Mining) with the Fourier Kolmogorov-Arnold Network (FourierKAN). The KAN architecture addresses limitations in traditional neural networks, improving model expressiveness and trainability. The model achieved F1-score of 84.80%, 93.12%, 90.02%, 82.10%, 87.90%, 83.14%, 78.58%, 89.93%, and 90.87% across nine public datasets. These results demonstrate that FRKAN-BioNER outperforms several prior state-of-the-art methods. Furthermore, its innovative architecture may hold potential for improving the efficiency of BioNER-relevant clinical text processing and could help accelerate knowledge mining from large-scale biomedical literature.

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Publication Details

Journal
npj Digital Medicine
Published
2026-04-27
DOI
https://doi.org/10.1038/s41746-026-02677-4
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
0.00

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article

Fourier Kolmogorov-Arnold Network integrated into BioBERT-based model for Biomedical Named Entity Recognition

立也 林, Guan Lixin, Xiaojun Xie, Li Mengshan et al.
npj Digital Medicine
Biomedical Text Mining and Ontologies
article

Fourier Kolmogorov-Arnold Network integrated into BioBERT-based model for Biomedical Named Entity Recognition

立也 林, Guan Lixin, Xiaojun Xie, Li Mengshan, Wu Yan, Zhu Jihong
article en

Abstract

Biomedical Named Entity Recognition (BioNER) extracts entities such as diseases, drugs, and genes from biomedical texts, which are often dense in domain-specific terms and complex semantics. Here, we present FRKAN-BioNER, a model designed to improve the efficiency of data mining in the biomedical field and support the development of precision medicine knowledge graphs. FRKAN-BioNER integrates BioBERT (Bidirectional Encoder Representations from Transformers for Biomedical Text Mining) with the Fourier Kolmogorov-Arnold Network (FourierKAN). The KAN architecture addresses limitations in traditional neural networks, improving model expressiveness and trainability. The model achieved F1-score of 84.80%, 93.12%, 90.02%, 82.10%, 87.90%, 83.14%, 78.58%, 89.93%, and 90.87% across nine public datasets. These results demonstrate that FRKAN-BioNER outperforms several prior state-of-the-art methods. Furthermore, its innovative architecture may hold potential for improving the efficiency of BioNER-relevant clinical text processing and could help accelerate knowledge mining from large-scale biomedical literature.

npj Digital Medicine
Gannan Normal University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 8%
Biomedical Text Mining and Ontologies
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Fourier Kolmogorov-Arnold Network integrated into BioBERT-based model for Biomedical Named Entity Recognition — 立也 林, Guan Lixin, et al. · npj Digital Medicine (2026) | TGRS Research Map | TGRS