Evaluating Basophil Histamine Content as a Biomarker for Omalizumab Responsiveness in Chronic Spontaneous Urticaria

Summary Our study confirms an association between basophil histamine content and features of type IIb CSU. However, this biomarker is not suitable for predicting omalizumab treatment response or treatment course.

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Publication Details

Journal
Clinical & Experimental Allergy
Published
2026-04-26
DOI
https://doi.org/10.1111/cea.70327
Primary Topic
Urticaria and Related Conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluating Basophil Histamine Content as a Biomarker for Omalizumab Responsiveness in Chronic Spontaneous Urticaria

Ditte Georgina Zhang, Simon Francis Thomsen, Per Stahl Skov, Clive Grattan et al.
Clinical & Experimental Allergy
Urticaria and Related Conditions
article

Evaluating Basophil Histamine Content as a Biomarker for Omalizumab Responsiveness in Chronic Spontaneous Urticaria

Ditte Georgina Zhang, Simon Francis Thomsen, Per Stahl Skov, Clive Grattan, Katrine Baumann
article en

Abstract

Summary Our study confirms an association between basophil histamine content and features of type IIb CSU. However, this biomarker is not suitable for predicting omalizumab treatment response or treatment course.

Clinical & Experimental Allergy
University of Copenhagen (DK), Guy's Hospital (GB), Bispebjerg Hospital (DK), Hvidovre Hospital (DK), St John's Hospital (GB)
Good health and well-being
Openalex Percentile: Top 8%
Urticaria and Related Conditions
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