Early regional splanchnic oxygen saturation and the development of necrotizing enterocolitis in preterm infants 28–32 weeks of gestation

BACKGROUND: in the first week after birth differ between preterm infants who later developed NEC and matched controls with a gestational age between 28 and 32 weeks or >32 weeks and a birth weight <1200 g. METHODS: CoVAR), and splanchnic-cerebral oxygenation ratio (SCOR) in the first week after birth. RESULTS: CoVAR was lower (0.10 [0.06-0.23] vs. 0.23 [0.14-0.26], P = 0.013) in infants who later developed NEC than in controls. CONCLUSION: CoVAR than matched controls on day seven after birth. These results suggest a different pathophysiology of NEC in this preterm group than preterm infants <28 weeks of gestation.

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Publication Details

Journal
Early Human Development
Published
2026-04-27
DOI
https://doi.org/10.1016/j.earlhumdev.2026.106574
Primary Topic
Infant Nutrition and Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Early regional splanchnic oxygen saturation and the development of necrotizing enterocolitis in preterm infants 28–32 weeks of gestation

Martin van der Heide, Sijmen A. Reijneveld, Roy E. Stewart, Jan B.F. Hulscher et al.
Early Human Development
Infant Nutrition and Health
article

Early regional splanchnic oxygen saturation and the development of necrotizing enterocolitis in preterm infants 28–32 weeks of gestation

Martin van der Heide, Sijmen A. Reijneveld, Roy E. Stewart, Jan B.F. Hulscher, Arend F. Bos, Elisabeth M.W. Kooi
article en

Abstract

BACKGROUND: in the first week after birth differ between preterm infants who later developed NEC and matched controls with a gestational age between 28 and 32 weeks or >32 weeks and a birth weight <1200 g. METHODS: CoVAR), and splanchnic-cerebral oxygenation ratio (SCOR) in the first week after birth. RESULTS: CoVAR was lower (0.10 [0.06-0.23] vs. 0.23 [0.14-0.26], P = 0.013) in infants who later developed NEC than in controls. CONCLUSION: CoVAR than matched controls on day seven after birth. These results suggest a different pathophysiology of NEC in this preterm group than preterm infants <28 weeks of gestation.

Early Human DevelopmentVol. 220
University Medical Center Groningen (NL), University of Groningen (NL)
Universitair Medisch Centrum Groningen
Zero hunger
Openalex Percentile: Top 18%
Infant Nutrition and Health
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