Optical coherence tomography measurements in retinopathy of prematurity: A systematic review and meta-analysis

= 0.002). OCT platform and geographic location also contributed to variability.ConclusionsIndividuals with prior ROP exhibit persistent, layer-specific and region-specific macular alterations consistent with disrupted neurovascular development and foveal hypoplasia. However, substantial methodological heterogeneity limits transportability of thickness-based biomarkers. Standardized, age-aware prospective OCT studies are required before structural metrics can be adopted for clinical risk stratification or longitudinal surveillance.