Genomic and functional approaches point to potential determinants of neonatal <i>K. pneumoniae</i> sepsis

-positive strains exhibit enhanced epithelial fitness and are associated with adverse clinical outcomes in this cohort. These findings highlight the importance of incorporating pathogen genomic and functional markers into neonatal sepsis research, surveillance, and future risk-stratification strategies.

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Publication Details

Journal
Microbiology Spectrum
Published
2026-04-27
DOI
https://doi.org/10.1128/spectrum.04118-25
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
0.00

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article

Genomic and functional approaches point to potential determinants of neonatal K. pneumoniae sepsis

Tapas Kumar Som, Manisha Rout, Soumitra Mohanty, Ashoka Mahapatra et al.
Microbiology Spectrum
Neonatal and Maternal Infections
article

Genomic and functional approaches point to potential determinants of neonatal K. pneumoniae sepsis

Tapas Kumar Som, Manisha Rout, Soumitra Mohanty, Ashoka Mahapatra, Saroj Kant Mohapatra, Subasini Majhi, Dharitri Mohapatra, S M K Mallick, Soumya Sibani Sahoo, Dr Jharana Mahanta, K Aksa Rani, V. Samuel Raj
article en

Abstract

-positive strains exhibit enhanced epithelial fitness and are associated with adverse clinical outcomes in this cohort. These findings highlight the importance of incorporating pathogen genomic and functional markers into neonatal sepsis research, surveillance, and future risk-stratification strategies.

Microbiology Spectrum
Sriram Chandra Bhanja Medical College Hospital (IN), Regional Centre for Biotechnology (IN), SRM University (IN), National Institute of Biomedical Genomics (IN), All India Institute of Medical Sciences (IN)
Department of Science and Technology, Ministry of Science and Technology, India
Good health and well-being
Openalex Percentile: Top 5%
Neonatal and Maternal Infections
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Genomic and functional approaches point to potential determinants of neonatal <i>K. pneumoniae</i> sepsis — Tapas Kumar Som, Manisha Rout, et al. · Microbiology Spectrum (2026) | TGRS Research Map | TGRS