Collective Behavior of Silica Nanoparticle Assemblies Governs Translocation Across Pulmonary Surfactant: From Synergistic Effects to Inhalation Toxicity
NPs dominate the overall behavior and significantly inhibit monolayer penetration. This work provides a systematic simulation framework for relating multi-NP architecture to translocation and PS disruption and may help generate testable hypotheses to guide future inhalation toxicology studies and nanomaterial research.
Authors
- 唐开亮
- Xinguang Cui (ORCID: https://orcid.org/0000-0002-0721-3119)
- Zhongnan An
- Haiwen Ge
- Honglin Hang
Institutions
- Zhejiang International Studies University (CN)
- Nano Carbon (Poland) (PL)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Langmuir
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/acs.langmuir.6c00061
- Primary Topic
- Inhalation and Respiratory Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China