Skin Hyperpigmentation: An Under‐Recognized Dermatological Clue to Vitamin B12 Deficiency
Cutaneous hyperpigmentation, an overlooked manifestation, can be an early sign of vitamin B12 deficiency. This case highlights symmetric pigmentation on the dorsum of hands and palms in a long-term vegetarian. Recognizing such subtle skin changes aids early diagnosis. Timely treatment reverses both pigmentation and systemic symptoms, underscoring its clinical relevance.
Authors
- Sandhya Regmi (ORCID: https://orcid.org/0009-0005-5844-8910)
- Sambidha Karki (ORCID: https://orcid.org/0009-0003-6438-1930)
- Nabita Bhattarai (ORCID: https://orcid.org/0009-0009-2859-0376)
- Sumit Paudel
- Mahesh Mathur
- Shilpa Maharjan
Institutions
- College of Medical Sciences (NP)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1002/ccr3.72634
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00