Faces and word forms can co-exist in right ventro-occipital temporal cortex – evidence from left-hemisphere perinatal stroke

This study informs our understanding of the causes and consequences of lateralization for visual object processing in ventro-occipitotemporal cortex (vOTC) by demonstrating that after a large perinatal stroke to the left hemisphere, faces and words can share right vOTC territory without compromise of neural or behavioral outcomes. This suggests that the lateralization pattern typically observed in neurologically healthy adults (left-lateralization of word forms and right-lateralization of faces) is unlikely to be driven solely by competition for left vOTC territory. It highlights the influence of other factors, such as intrahemispheric connectivity and asymmetrical hemispheric processing preferences, in determining hemispheric lateralization for face processing.

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Publication Details

Journal
Journal of Neuroscience
Published
2026-04-27
DOI
https://doi.org/10.1523/jneurosci.1854-25.2026
Primary Topic
Face Recognition and Perception
Type
article
Field-Weighted Citation Impact
0.00

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article

Faces and word forms can co-exist in right ventro-occipital temporal cortex – evidence from left-hemisphere perinatal stroke

Elissa L. Newport, Barbara Landau, Kasey Stack, Anna Seydell‐Greenwald et al.
Journal of Neuroscience
Face Recognition and Perception
article

Faces and word forms can co-exist in right ventro-occipital temporal cortex – evidence from left-hemisphere perinatal stroke

Elissa L. Newport, Barbara Landau, Kasey Stack, Anna Seydell‐Greenwald, Catherine E. Chambers
article en

Abstract

This study informs our understanding of the causes and consequences of lateralization for visual object processing in ventro-occipitotemporal cortex (vOTC) by demonstrating that after a large perinatal stroke to the left hemisphere, faces and words can share right vOTC territory without compromise of neural or behavioral outcomes. This suggests that the lateralization pattern typically observed in neurologically healthy adults (left-lateralization of word forms and right-lateralization of faces) is unlikely to be driven solely by competition for left vOTC territory. It highlights the influence of other factors, such as intrahemispheric connectivity and asymmetrical hemispheric processing preferences, in determining hemispheric lateralization for face processing.

Journal of Neuroscience
Johns Hopkins University (US), Georgetown University (US), Georgetown University Medical Center (US)
National Institutes of Health, National Institute on Deafness and Other Communication Disorders
Quality Education
Openalex Percentile: Top 17%
Face Recognition and Perception
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