Multicomponent C−H Activation/Annulation Polymerizations Toward Structurally Regular Polyelectrolytes With Light‐Boosted Antibacterial Potency

up to 224700 g/mol) in good yields (up to 91.2%). The resulting polyelectrolytes exhibited excellent solubility and readily tunable photophysical properties, with fluorescence emission extending to the first near-infrared region. Moreover, these structurally regular conjugated polyelectrolytes exhibit synergistic photothermal and photodynamic effects, achieving potent light-enhanced antibacterial and antibiofilm activities against both Gram-positive and Gram-negative bacteria, including drug-resistant strains. This work provides a versatile polymerization platform for the precise synthesis of diverse functional polyelectrolytes with promising applications in optoelectronics and antimicrobial therapeutics.