Development of a Highly Sensitive <sup>31</sup> P{ <sup>1</sup> H} NMR-Based Method for Trace-Level Detection of Alkylphosphonic Acids as Environmental Markers of Deadly Nerve Agents

H} NMR signatures at trace levels in aqueous matrices. The key experimental approach of the developed method is unique and in line with the requirements of OPTs of OPCW, with an achievable detection limit of APAs at ≥1.0 μg/mL levels in complex environmental matrices. The developed method is of great relevance, especially in CWC verification and forensic analysis of APAs at trace levels.

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Publication Details

Journal
Analytical Chemistry
Published
2026-04-27
DOI
https://doi.org/10.1021/acs.analchem.5c07492
Primary Topic
Pesticide Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
0.00
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article

Development of a Highly Sensitive 31 P{ 1 H} NMR-Based Method for Trace-Level Detection of Alkylphosphonic Acids as Environmental Markers of Deadly Nerve Agents

Ajay Kumar Purohit, Mohammed Mohsin, Meehir Palit, Sweeti et al.
Analytical Chemistry
Pesticide Exposure and Toxicity
article

Development of a Highly Sensitive 31 P{ 1 H} NMR-Based Method for Trace-Level Detection of Alkylphosphonic Acids as Environmental Markers of Deadly Nerve Agents

Ajay Kumar Purohit, Mohammed Mohsin, Meehir Palit, Sweeti, Ajeet Kumar
article en

Abstract

H} NMR signatures at trace levels in aqueous matrices. The key experimental approach of the developed method is unique and in line with the requirements of OPTs of OPCW, with an achievable detection limit of APAs at ≥1.0 μg/mL levels in complex environmental matrices. The developed method is of great relevance, especially in CWC verification and forensic analysis of APAs at trace levels.

Analytical Chemistry
Defence Research and Development Establishment (IN), Versar (United States) (US)
Openalex Percentile: Top 11%
Pesticide Exposure and Toxicity
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