Laboratory Assessment and Clinical Outlook for <i>Ex Vivo</i> -Produced Human Platelets and Megakaryocytes from Stem Cell Sources
circulation of platelet products. Initial implementation will likely focus on high-value applications, such as transfusion for alloimmunized patients, before broader adoption. The long-term goal is to replace the vulnerable donor-dependent system with on-demand production of standardized, pathogen-free, and universally compatible platelets.
Authors
- Dae‐Hyun Ko (ORCID: https://orcid.org/0000-0002-9781-0928)
- Soon Sung Kwon (ORCID: https://orcid.org/0000-0002-7000-9284)
- Hyun Ok Kim (ORCID: https://orcid.org/0000-0002-4964-1963)
- Yong Gon Cho (ORCID: https://orcid.org/0000-0003-3011-6875)
- Seung Yeob Lee (ORCID: https://orcid.org/0000-0003-2851-1112)
- Sinyoung Kim (ORCID: https://orcid.org/0000-0002-2609-8945)
- Kyoung Mi Kim (ORCID: https://orcid.org/0000-0002-2845-5678)
- Koudai I Albaira
- Hyung Jin Kim (ORCID: https://orcid.org/0009-0008-2310-006X)
- Jaecheol Lee (ORCID: https://orcid.org/0000-0002-2070-7463)
Institutions
- Ulsan College (KR)
- Yonsei University (KR)
- Korean Red Cross (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Jeonbuk National University Hospital (KR)
- Jeonbuk National University (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Annals of Laboratory Medicine
- Published
- 2026-04-27
- DOI
- https://doi.org/10.3343/alm.2025.0687
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Trade, Industry and Energy
- Ministry of Food and Drug Safety
- Ministry of Health and Welfare
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- Jeonbuk National University