Modular Synthesis of Chiral Tetrasubstituted Allylic Amines via Nickel-Catalyzed Enantioselective Difunctionalization of Alkynes with Imines and Arylboronic Acids
-sulfonylimines and arylboronic reagents. This asymmetric three-component transformation furnished a wide range of enantioenriched tetrasubstituted allylic amines with excellent regioselectivity and stereoselectivity under mild conditions.
Authors
- Fangfang Feng (ORCID: https://orcid.org/0009-0009-6822-5779)
- Haitao Yu
- Zhuojia Hou
- Shuojia Li
- Xiaojuan Wang
- Xiruo Han
- Yongbing Liu (ORCID: https://orcid.org/0009-0000-0021-2634)
Institutions
- Laboratoire de Synthèse Organique (FR)
- Advanced Materials and Devices (United States) (US)
- Hebei Normal University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/acs.orglett.6c01015
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hebei Normal University
- Natural Science Foundation of Hebei Province
- Hebei Provincial Department of Bureau of Science and Technology