Transcriptional and epigenetic plasticity drive an alternative non-clonal mechanism of resistance to KRASG12D inhibition in pancreatic cancer

Transcriptional and epigenetic plasticity drive an alternative non-clonal mechanism of resistance to KRASG12D inhibition in pancreatic cancer

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Publication Details

Journal
Cancer Communications
Published
2026-04-26
DOI
https://doi.org/10.34133/cancomm.0030
Primary Topic
Protein Kinase Regulation and GTPase Signaling
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptional and epigenetic plasticity drive an alternative non-clonal mechanism of resistance to KRASG12D inhibition in pancreatic cancer

Stefano Ugel, Carmine Carbone, Lorenzo Priori, Alessia Caggiano et al.
Cancer Communications
Protein Kinase Regulation and GTPase Signaling
article

Transcriptional and epigenetic plasticity drive an alternative non-clonal mechanism of resistance to KRASG12D inhibition in pancreatic cancer

Stefano Ugel, Carmine Carbone, Lorenzo Priori, Alessia Caggiano, Claudio Sette, Vincenzo Corbo, Gian Luca Rampioni Vinciguerra, Geny Piro, Giampaolo Tortora, Vincenzo Bronte, Davide Pasini, Annachiara Esposito, Antonio Agostini, Federica Cinti, Diego de la Rosa, Francesco De Sanctis, Diego Iacuone, Anna Ceccarelli
article en

Abstract

Transcriptional and epigenetic plasticity drive an alternative non-clonal mechanism of resistance to KRASG12D inhibition in pancreatic cancer

Cancer Communications
Agostino Gemelli University Polyclinic (IT)
Good health and well-being
Openalex Percentile: Top 18%
Protein Kinase Regulation and GTPase Signaling
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Transcriptional and epigenetic plasticity drive an alternative non-clonal mechanism of resistance to KRASG12D inhibition in pancreatic cancer — Stefano Ugel, Carmine Carbone, et al. · Cancer Communications (2026) | TGRS Research Map | TGRS