Biomedical CoCrMo/HA Composite Prepared by 3D Printing

Traditional biomedical metallic materials, such as Ti, Ti alloys, and CoCrMo alloy, have high density and relatively limited biocompatibility, which would affect human bone repair. In this work, the CoCrMo/hydroxyapatite (HA) composite for biomedical applications is synthesized by the three-dimensional (3D) printing technology. The biocompatibility, blood compatibility, and mechanical properties are investigated in detail. The composite with 50 vol % HA exhibits good biocompatibility and blood compatibility, superior to commonly used medical materials. And this advantage tends to be more obvious with the extension of the duration. Meanwhile, the CoCrMo/HA composite can maintain a compressive strength of 724.4 MPa, which meets the requirement of human bone repair. This work provides a reference for the preparation of biomedical composites, and the as-formed composites may become a new choice for bone repair.

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Publication Details

Journal
ACS Biomaterials Science & Engineering
Published
2026-04-27
DOI
https://doi.org/10.1021/acsbiomaterials.6c00501
Primary Topic
Bone Tissue Engineering Materials
Type
article
Field-Weighted Citation Impact
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article

Biomedical CoCrMo/HA Composite Prepared by 3D Printing

Tadashi Fujieda, Jinzhi Ren, Hao Wang, Shengli Zhu et al.
ACS Biomaterials Science & Engineering
Bone Tissue Engineering Materials
article

Biomedical CoCrMo/HA Composite Prepared by 3D Printing

Tadashi Fujieda, Jinzhi Ren, Hao Wang, Shengli Zhu, S Wang, Qianying Guo, Akihiko Chiba
article en

Abstract

Traditional biomedical metallic materials, such as Ti, Ti alloys, and CoCrMo alloy, have high density and relatively limited biocompatibility, which would affect human bone repair. In this work, the CoCrMo/hydroxyapatite (HA) composite for biomedical applications is synthesized by the three-dimensional (3D) printing technology. The biocompatibility, blood compatibility, and mechanical properties are investigated in detail. The composite with 50 vol % HA exhibits good biocompatibility and blood compatibility, superior to commonly used medical materials. And this advantage tends to be more obvious with the extension of the duration. Meanwhile, the CoCrMo/HA composite can maintain a compressive strength of 724.4 MPa, which meets the requirement of human bone repair. This work provides a reference for the preparation of biomedical composites, and the as-formed composites may become a new choice for bone repair.

ACS Biomaterials Science & Engineering
Institute for Creation Research (US), Hatch (Canada) (CA), Tianjin University (CN), Shimane University (JP), Tohoku University (JP)
Openalex Percentile: Top 8%
Bone Tissue Engineering Materials
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