EVALUATION OF LABORATORY AND IMAGING PARAMETERS IN PATIENTS UNDERGOING OPEN HEART SURGERY

Objective: Coronary artery bypass grafting (CABG) remains a widely performed surgical intervention for coronary artery disease. Despite advances in perioperative care and preoperative risk stratification, postoperative complications and mortality continue to pose significant clinical challenges. This study aimed to investigate the prognostic value of platelet related parameters specifically, mean platelet volume (MPV) and platelet count (PLT) in predicting postoperative outcomes and 30-day mortality in patients undergoing CABG. Material and Methods: This retrospective, single-center study included 406 adult patients who presented to the emergency department with acute coronary syndrome and subsequently underwent isolated CABG between 2019 and 2023. Demographic characteristics, preoperative EuroSCORE II and logEuroSCORE values, laboratory parameters and echocardiographic findings were recorded. Postoperative outcomes included 30-day mortality, major adverse cardiac events (MACE) and composite poor outcomes. Hematologic and biochemical parameters were analyzed at admission and on postoperative day 30 or the day of death. Associations between these variables and clinical outcomes were assessed using ROC and regression analyses. Results: Among the 406 patients (mean age: 63.5±8.6 years; 76.1% male), the 30-day mortality rate was 4.7%, with MACE and poor outcomes occurring in 9.4% and 10.1% of cases, respectively. Postoperative MPV and PLT were significantly associated with all outcome groups (p