Unilateral proptosis as the manifestation of euthyroid Graves orbitopathy: A case report

RATIONALE: To report a case of Euthyroid Graves' disease with Unilateral eye involvement and its diagnostic and management challenges. PATIENT CONCERNS: A 36-year-old female with left eye proptosis. DIAGNOSES: CECT and MRI reported the proptosis of the left eye with thickening of the left extraocular muscles without the involvement of the tendons, without a focal lesion, with mild hyperintensity and mild diffuse enhancement representing unilateral thyroid ophthalmopathy. INTERVENTIONS: CECT and MRI for the diagnosis. IV methylprednisolone for the management. OUTCOMES: Complete resolution of symptoms by 6 months. LEARNINGS: 1) Although commonly hyperthyroid, patients with Graves' disease may be euthyroid. 2) Graves' orbitopathy can affect the unilateral eye. 3) Long-term follow-up and joint endocrine and ophthalmology teamwork required for effective management.

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Publication Details

Journal
Medicine
Published
2026-04-24
DOI
https://doi.org/10.1097/md.0000000000048416
Primary Topic
Ophthalmology and Eye Disorders
Type
article
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article

Unilateral proptosis as the manifestation of euthyroid Graves orbitopathy: A case report

Somee Rauniyar, Sonam Dhenga, Milan Pokhrel, Bibek Shrestha et al.
Medicine
Ophthalmology and Eye Disorders
article

Unilateral proptosis as the manifestation of euthyroid Graves orbitopathy: A case report

Somee Rauniyar, Sonam Dhenga, Milan Pokhrel, Bibek Shrestha, Ganesh Chaudhary
article en

Abstract

RATIONALE: To report a case of Euthyroid Graves' disease with Unilateral eye involvement and its diagnostic and management challenges. PATIENT CONCERNS: A 36-year-old female with left eye proptosis. DIAGNOSES: CECT and MRI reported the proptosis of the left eye with thickening of the left extraocular muscles without the involvement of the tendons, without a focal lesion, with mild hyperintensity and mild diffuse enhancement representing unilateral thyroid ophthalmopathy. INTERVENTIONS: CECT and MRI for the diagnosis. IV methylprednisolone for the management. OUTCOMES: Complete resolution of symptoms by 6 months. LEARNINGS: 1) Although commonly hyperthyroid, patients with Graves' disease may be euthyroid. 2) Graves' orbitopathy can affect the unilateral eye. 3) Long-term follow-up and joint endocrine and ophthalmology teamwork required for effective management.

MedicineVol. 105(17)
Tribhuvan University Teaching Hospital (NP)
Openalex Percentile: Top 16%
Ophthalmology and Eye Disorders
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