Novel Indoline Derivatives Serotonergic Psychedelic Agents as 5-HT2A Agonists for Treating Psychosis, Mental Illness and CNS Disorders

Provided herein are novel indoline derivatives serotonergic psychedelic agents as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders and processes for preparing such compounds.

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Publication Details

Journal
ACS Medicinal Chemistry Letters
Published
2026-04-27
DOI
https://doi.org/10.1021/acsmedchemlett.6c00208
Primary Topic
Psychedelics and Drug Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Novel Indoline Derivatives Serotonergic Psychedelic Agents as 5-HT2A Agonists for Treating Psychosis, Mental Illness and CNS Disorders

Ram W. Sabnis, Anika R. Sabnis
ACS Medicinal Chemistry Letters
Psychedelics and Drug Studies
article

Novel Indoline Derivatives Serotonergic Psychedelic Agents as 5-HT2A Agonists for Treating Psychosis, Mental Illness and CNS Disorders

Ram W. Sabnis, Anika R. Sabnis
article en

Abstract

Provided herein are novel indoline derivatives serotonergic psychedelic agents as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating psychosis, mental illness and central nervous system (CNS) disorders and processes for preparing such compounds.

ACS Medicinal Chemistry Letters
Mayo Clinic (US)
Good health and well-being
Openalex Percentile: Top 5%
Psychedelics and Drug Studies
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