Epitranscriptomic regulation of mRNA stability in pivotal transcription factors modulates the second cell fate decision

A-dependent post-transcriptional regulation plays a pivotal role in shaping lineage specification during peri-implantation and provided potential strategies for rescuing developmental defects.

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Publication Details

Journal
Nature Communications
Published
2026-04-28
DOI
https://doi.org/10.1038/s41467-026-72131-2
Primary Topic
RNA Research and Splicing
Type
article
Field-Weighted Citation Impact
0.00

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article

Epitranscriptomic regulation of mRNA stability in pivotal transcription factors modulates the second cell fate decision

Weide Xiao, Yawei Gao, Xiaochen Kou, Jun Liu et al.
Nature Communications
RNA Research and Splicing
article

Epitranscriptomic regulation of mRNA stability in pivotal transcription factors modulates the second cell fate decision

Weide Xiao, Yawei Gao, Xiaochen Kou, Jun Liu, Jiaxu Lu, Yanhong Zhao, Kuisheng Liu, Lei Yang, Shaorong Gao, Zhile Bai, Mingli Ma, Li TANG, Xuelian Liu, Wenqing Ding, Hong Wang
article en

Abstract

A-dependent post-transcriptional regulation plays a pivotal role in shaping lineage specification during peri-implantation and provided potential strategies for rescuing developmental defects.

Nature Communications
Tongji University (CN), Peking University (CN), Shanghai East Hospital (CN), Shanghai First Maternity and Infant Hospital (CN), CNS Research (United States) (US), Center for Life Sciences (CN)
National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, Peking University, Shenzhen Bay Laboratory, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities
Zero hunger
Openalex Percentile: Top 8%
RNA Research and Splicing
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Epitranscriptomic regulation of mRNA stability in pivotal transcription factors modulates the second cell fate decision — Weide Xiao, Yawei Gao, et al. · Nature Communications (2026) | TGRS Research Map | TGRS