Targeted Biomimetic Stem Cell Membrane–Exosome Composite Delivery System for the Treatment of Bone Defects
exerts its therapeutic effects by activating the TGF-β signaling pathway. These findings highlight an integration strategy for exosome-based therapy and offer a promising approach to overcoming current limitations in bone defect treatment, with substantial potential for clinical translation.
Authors
- Min Xu (ORCID: https://orcid.org/0000-0002-6638-1454)
- Hongwei Pang
- Jie Yu
- Bin Guo (ORCID: https://orcid.org/0000-0003-1738-3370)
- Chong Yin
- Wei Chen
- Binxin Wang
- Ning Xie
Institutions
- Shihezi University (CN)
- North Sichuan Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
- Translational Research in Oncology (FR)
- County Hospital (GB)
- Center for Translational Molecular Medicine (NL)
Publication Details
- Journal
- ACS Applied Materials & Interfaces
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/acsami.5c24575
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China