Grafting copolymerization of N-vinylcaprolactam and N, N-dimethylacrylamide onto medical-grade silicone rubber catheters by gamma rays

Abstract In this research, we propose modifying medical SR catheters through radiation grafting of N -vinylcaprolactam (NVCL) and N,N -dimethylacrylamide (DMAAm) to improve the its properties by imparting it thermoresponsiveness and high hydrophilicity. The reaction parameters were studied to verify their effect on the grafting degree and the apparent mechanical properties of the SR catheter. The grafting of NVCL and DMAAm into SR catheters were verified by means of infrared spectroscopy (FTIR-ATR), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), swelling tests, and contact angle. The results confirmed that the graft copolymer exhibits an LCST of 44°C, swelling capacity, and water affinity. Graphical abstract