In-situ product recovery in microfluidic bioreactors

produced by cyanobacteria in a microfluidic reactor is used to benchmark productivities through process simulations. In general, the productivity of microfluidic bioprocesses is confined by biocatalytic reaction rates, diffusion rates, and residence time. Key challenges for scale-up, and thus achieving high space-time yields, comprise biocatalyst formats, catalytic robustness, and specific turn-over rates, as well as numbering-up of microfluidic devices. Economically and physically accessible application areas may thus be limited to milligram or higher gram quantities of specialty products.