Bile Drainage Improves Survival in Amatoxin-induced Severe Liver Injury: A Prospective Pilot Cohort Study
Amatoxin-containing mushroom poisoning causes fatal acute liver failure with >50% mortality despite maximal medical therapy. Interrupting the enterohepatic recirculation of amatoxins is a mechanistically rational but unproven therapeutic strategy. This study aimed to evaluate the efficacy and safety of biliary drainage (BD) in patients with pre-liver failure caused by amatoxin-containing mushroom poisoning.
Authors
- Xiuying Ma (ORCID: https://orcid.org/0000-0001-6749-1965)
- Jiawei Geng (ORCID: https://orcid.org/0000-0002-9122-1532)
- Wei Yue (ORCID: https://orcid.org/0000-0002-7444-2026)
- Yuan Shen
- Bin Han (ORCID: https://orcid.org/0000-0003-3653-0305)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2026-04-27
- DOI
- https://doi.org/10.14218/jcth.2026.00057
- Primary Topic
- Silymarin and Mushroom Poisoning
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- General Hospital of People’s Liberation Army