Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds

) were treated with acellular fish skin graft. Wound healing was assessed by photographic documentation, confocal microscopy and clinical evaluation. Patient satisfaction was assessed using a structured questionnaire. A positive effect on wound healing, defined as a reduction in wound size, was observed in 88.6% of cases, with complete wound closure in 45.45% of cases. Most patients reported that the procedure was neither painful nor time-intensive; 95% stated that they would opt for treatment again. Fish skin grafting has also shown beneficial outcomes in complex cases, such as in wounds secondary to pyoderma gangrenosum and wounds with exposed bone. Fish skin graft transplantation represents a safe, well-tolerated and effective option for managing chronic wounds as well as challenging postoperative wounds, such as those at anatomically challenging sites.

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Publication Details

Journal
International Wound Journal
Published
2026-04-27
DOI
https://doi.org/10.1111/iwj.70931
Primary Topic
Wound Healing and Treatments
Type
article
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article

Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds

C Böddeker, Norman‐Philipp Hoff, Bernhard Homey, Sarah Biermann et al.
International Wound Journal
Wound Healing and Treatments
article

Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds

C Böddeker, Norman‐Philipp Hoff, Bernhard Homey, Sarah Biermann, T Jansen
article en

Abstract

) were treated with acellular fish skin graft. Wound healing was assessed by photographic documentation, confocal microscopy and clinical evaluation. Patient satisfaction was assessed using a structured questionnaire. A positive effect on wound healing, defined as a reduction in wound size, was observed in 88.6% of cases, with complete wound closure in 45.45% of cases. Most patients reported that the procedure was neither painful nor time-intensive; 95% stated that they would opt for treatment again. Fish skin grafting has also shown beneficial outcomes in complex cases, such as in wounds secondary to pyoderma gangrenosum and wounds with exposed bone. Fish skin graft transplantation represents a safe, well-tolerated and effective option for managing chronic wounds as well as challenging postoperative wounds, such as those at anatomically challenging sites.

International Wound JournalVol. 23(5)
Düsseldorf University Hospital (DE), Heinrich Heine University Düsseldorf (DE)
Life below water
Openalex Percentile: Top 9%
Wound Healing and Treatments
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