K <sub>2</sub> S <sub>2</sub> O <sub>8</sub> -Mediated Bromination/Truce–Smiles Rearrangement/Desulfonylation of <i>N</i> -Arylsulfonyl Acrylamides: Access to β-Brominated Amide Derivatives
-brominated amides containing a quaternary carbon center in good yields. Mechanistic studies indicated that the formation of bromine radicals represents the crucial step in this radical cascade transformation. This approach provides a complementary and efficient route toward the synthesis of valuable β-brominated amide derivatives.
Authors
- Hai‐Tao Zhu (ORCID: https://orcid.org/0000-0003-1200-962X)
- Dongfang Jiang (ORCID: https://orcid.org/0009-0006-3644-7519)
- Jiaming Huang (ORCID: https://orcid.org/0000-0001-7416-7813)
- Jiale Liu (ORCID: https://orcid.org/0000-0002-8609-580X)
- Qiumei Yin
- Yucai Tang (ORCID: https://orcid.org/0000-0002-2203-4039)
- Na Long
- Wei-Min He (ORCID: https://orcid.org/0000-0002-9481-6697)
- Jingyao Liang
Institutions
- Changsha Medical University (CN)
- Hunan University of Arts and Science (CN)
- Baoji University of Arts and Sciences (CN)
- Material (Belgium) (BE)
- Nomura Plating (Japan) (JP)
- University of South China (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-04-27
- DOI
- https://doi.org/10.1021/acs.joc.6c00337
- Primary Topic
- Vanadium and Halogenation Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Scientific Research Foundation of Hunan Provincial Education Department